Alexander Disease Research Update – Episode #24: 1) iPS cell model with aberrant development and 2) unusual variant in GFAP affecting the eye

Albee Messing and Natasha Snider discuss the following recent publications: 

[01:04]       Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease
                  Glia (2024) (in press)

[16:46]       A novel GFAP frameshift variant identified in a family with optico-retinal dysplasia and vision impairment
Human Molecular Genetics (2024) (in press)

Send your questions and feedback to:  amessing@wisc.edu

Help support research on Alexander Disease at the University of Wisconsin-Madison's Waisman Center:

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Chapters

• 1:04 Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease
• 16:46 A novel GFAP frameshift variant identified in a family with optico-retinal dysplasia and vision impairment