Alexander Disease Research Update
Discussion of recent publications from the research literature on Alexander Disease, hosted by Albee Messing from the University of Wisconsin-Madison.
Alexander Disease Research Update
Latest Episodes
Alexander Disease Research Update – Episode #33: Can Initial MRI and Two Motor Milestones Predict Trajectory of Disease?
Albee Messing and Ylenia Vaia discuss the following recent publication: Neuroradiological patterns and prognostic implications in type I Alexander diseaseMolecular Genetics and Metabolism, 148, 110189 (...
Alexander Disease Research Update – Episode #32: 1) GFAP variants and oxidative stress, and 2) GFAP variants and lysosomes
Albee Messing, Dolores Pérez-Sala, and Natasha Snider discuss the following recent publications: Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational m...
Alexander Disease Research Update – Episode #31: 1) Development of an AxD Severity Score, and 2) Peer review – please come home
Albee Messing, Annette Bley, and Nadia Kokaly discuss the following recent publication: [01:58] Description of the Hamburg Alexander Leukodystrophy Cohort-Insights into Practical Classi...
Alexander Disease Research Update – Episode #30: 1) Speech-language impairments, and 2) GFAP concentrations in CSF and blood
Albee Messing, Debra Levin, and Amy Waldman discuss the following recent publications: [01:27] Language Skills in Patients With Alexander Disease. American Journal of Sp...
Alexander Disease Research Update - Episode #29: Genotype-phenotype correlations, or does variant predict course?
Albee Messing and Amanda Nagy discuss the following recent publication: [01:42] Genotype-phenotype correlations of GFAP variants in type I Alexander disease subtypesMolecular Geneti...