Alexander Disease Research Update
Discussion of recent publications from the research literature on Alexander Disease, hosted by Albee Messing from the University of Wisconsin-Madison.
Alexander Disease Research Update
Latest Episodes
Alexander Disease Research Update, Episode #35: When a Doctor is a Patient
Albee Messing and Aidan Long discuss the following recent publication: Demonstrating clinical and radiological variability of adult-onset Alexander disease in three siblings &nb...
AxDRU Episode #34: AxD rats have problems with eating and speaking
Albee Messing, Jared Cullen, and Nadine Connor discuss the following recent publication: Behavioral characterization of bulbar sensorimotor function in a rat model of Alexander disease ...
Alexander Disease Research Update – Episode #33: Can Initial MRI and Two Motor Milestones Predict Trajectory of Disease?
Albee Messing and Ylenia Vaia discuss the following recent publication: Neuroradiological patterns and prognostic implications in type I Alexander diseaseMolecular Genetics and Metabolism, 148, 110189 (...
Alexander Disease Research Update – Episode #32: 1) GFAP variants and oxidative stress, and 2) GFAP variants and lysosomes
Albee Messing, Dolores Pérez-Sala, and Natasha Snider discuss the following recent publications: Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational m...
Alexander Disease Research Update – Episode #31: 1) Development of an AxD Severity Score, and 2) Peer review – please come home
Albee Messing, Annette Bley, and Nadia Kokaly discuss the following recent publication: [01:58] Description of the Hamburg Alexander Leukodystrophy Cohort-Insights into Practical Classi...